Genomics Reporting Implementation Guide
3.0.0 - STU3 International flag

Publication Build: This will be filled in by the publication tooling

Example Task: MedicationRecommendationExample1

Generated Narrative: Task MedicationRecommendationExample1

status: Requested

intent: proposal

code: Consider alternative medication

description: Patients positive for this allele should not be treated with CBZ, unless the benefits clearly outweigh the risk. Therapy should be discontinued immediately if symptoms of SJS or TEN develop. Alternative medication should be used as first line therapy. Consideration in the choice for alternative medications should be given to potential cross-reactivity with structurally similar aromatic antiepileptic drugs such as oxcarbazepine, phenytoin, fosphenytoin and lamotrigine, which can also moderately increase risk for SJS/TEN in association with HLA-B*15:02 positivity.

for: Adam B. Everyman Male, DoB: 1951-01-20 ( Medical Record Number: m123 (use: usual, ))

reasonReference: Observation Therapeutic Implication