COVID-19 FHIR Profile Library IG Informative Version
1.0.0 - Informative US

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## ValueSet: COVID-19 metabolic underlying condition reference set

Official URL: http://hl7.org/fhir/us/covid19library/ValueSet/covid19-underlying-metabolic-condition-value-set | Version: 1.0.0
Active as of 2022-07-25 | Computable Name: COVID19UnderlyingMetabolicConditionVS
Copyright/Legal: This value set includes content from SNOMED CT, which is copyright © 2002+ International Health Terminology Standards Development Organisation (IHTSDO), and distributed by agreement between IHTSDO and HL7. Implementer use of SNOMED CT is not covered by this agreement

A set of codes that describe underlying metabolic conditions for COVID19

References

- COVID-19 Underlying Medical Condition observation
- COVID-19 metabolic underlying condition

### Logical Definition (CLD)

- Include these codes as defined in `http://snomed.info/sct`

  Code | Display
  267454002 | Acatalasemia (disorder)
  238069004 | Acyl-coenzyme A oxidase deficiency (disorder)
  363732003 | Addison's disease (disorder)
  386584007 | Adrenal cortical hypofunction (disorder)
  237735008 | Adrenal Cushing's syndrome (disorder)
  65389002 | Adrenoleukodystrophy (disorder)
  700463002 | Alpha-methylacyl-CoA racemase deficiency disorder (disorder)
  54954004 | Aspartylglucosaminuria (disorder)
  238068007 | Bifunctional peroxisomal enzyme deficiency (disorder)
  128289001 | Chronic metabolic disorder (disorder)
  7573000 | Classical phenylketonuria (disorder)
  35691006 | Combined deficiency of sialidase AND beta galactosidase (disorder)
  237751000 | Congenital adrenal hyperplasia (disorder)
  419097006 | Danon disease (disorder)
  124302001 | Deficiency of galactokinase (disorder)
  124437004 | Deficiency of glucose-6-phosphatase (disorder)
  124335006 | Deficiency of phosphoglycerate kinase (disorder)
  124675005 | Deficiency of phosphoglycerate mutase (disorder)
  387817006 | Deficiency of phosphorylase b kinase (disorder)
  124329006 | Deficiency of phosphorylase kinase (disorder)
  46635009 | Diabetes mellitus type 1 (disorder)
  44054006 | Diabetes mellitus type 2 (disorder)
  73211009 | Diabetes mellitus (disorder)
  45744005 | Disorder of mineral metabolism (disorder)
  238059005 | Disorder of peroxisomal function (disorder)
  238006008 | Disorder of purine and pyrimidine metabolism (disorder)
  30171000 | Disorder of adrenal gland (disorder)
  73132005 | Disorder of parathyroid gland (disorder)
  399244003 | Disorder of pituitary gland (disorder)
  190680002 | Disorders of amino acid transport and metabolism (disorder)
  16652001 | Fabry's disease (disorder)
  79935000 | Farber's lipogranulomatosis (disorder)
  717276003 | Folinic acid responsive seizure syndrome (disorder)
  20052008 | Fructose-1,6-bisphosphate aldolase B deficiency (disorder)
  28183005 | Fructose-biphosphatase deficiency (disorder)
  190745006 | Galactosemia (disorder)
  192782005 | Galactosylceramide beta-galactosidase deficiency (disorder)
  190794006 | Glucosylceramide beta-glucosidase deficiency (disorder)
  235908005 | Glycogen storage disease type IX (disorder)
  41527003 | Glycogen storage disease type VIII (disorder)
  37666005 | Glycogen storage disease type X (disorder)
  717821004 | Glycogen storage disease with severe cardiomyopathy due to glycogenin deficiency (disorder)
  7265005 | Glycogen storage disease, type I (disorder)
  274864009 | Glycogen storage disease, type II (disorder)
  66937008 | Glycogen storage disease, type III (disorder)
  11179002 | Glycogen storage disease, type IV (disorder)
  55912009 | Glycogen storage disease, type V (disorder)
  29291001 | Glycogen storage disease, type VI (disorder)
  89597008 | Glycogen storage disease, type VII (disorder)
  237964009 | Glycogen synthase deficiency (disorder)
  61598006 | Glycogenosis with glucoaminophosphaturia (disorder)
  238025006 | GM1 gangliosidosis (disorder)
  353295004 | Graves' disease (disorder)
  21983002 | Hashimoto thyroiditis (disorder)
  111578003 | Hereditary nonspherocytic hemolytic anemia due to aldolase A deficiency (disorder)
  66999008 | Hyperparathyroidism (disorder)
  10649000 | Hyperpituitarism (disorder)
  34486009 | Hyperthyroidism (disorder)
  36976004 | Hypoparathyroidism (disorder)
  74728003 | Hypopituitarism (disorder)
  40930008 | Hypothyroidism (disorder)
  70199000 | I-cell disease (disorder)
  86095007 | Inborn error of metabolism (disorder)
  238062008 | Infantile Refsum's disease (disorder)
  18756002 | Juvenile GM1 gangliosidosis (disorder)
  65524005 | Mannosidosis (disorder)
  27718001 | Maple syrup urine disease (disorder)
  69463008 | Maroteaux-Lamy syndrome (disorder)
  237602007 | Metabolic syndrome X (disorder)
  396338004 | Metachromatic leucodystrophy (disorder)
  725296006 | Mucolipidosis type IV (disorder)
  75610003 | Mucopolysaccharidosis type I (disorder)
  65327002 | Mucopolysaccharidosis type I-H (disorder)
  26745009 | Mucopolysaccharidosis type I-H/S (disorder)
  70737009 | Mucopolysaccharidosis type II (disorder)
  73123008 | Mucopolysaccharidosis type I-S (disorder)
  43916004 | Mucopolysaccharidosis type VII (disorder)
  378007 | Morquio syndrome (disorder)
  238061001 | Neonatal adrenoleucodystrophy (disorder)
  783717008 | Phosphoglucomutase 1-related congenital disorder of glycosylation (disorder)
  5335002 | Phosphoenolpyruvate carboxykinase deficiency (disorder)
  25362006 | Phytanic acid storage disease (disorder)
  65520001 | Primary hyperoxaluria, type I (disorder)
  65764006 | Pseudo-Hurler polydystrophy (disorder)
  734434007 | Pyridoxine-dependent epilepsy (disorder)
  46683007 | Pyruvate dehydrogenase complex deficiency (disorder)
  23849003 | Sandhoff disease (disorder)
  88393000 | Sanfilippo syndrome (disorder)
  38795005 | Sialidosis (disorder)
  58459009 | Sphingomyelin/cholesterol lipidosis (disorder)
  34420000 | Storage disease (disorder)
  367368009 | Sulfite oxidase deficiency (disorder)
  111385000 | Tay-Sachs disease (disorder)
  264580006 | Thyroid dysfunction (disorder)
  8849004 | Uridine diphosphate glucose-4-epimerase deficiency (disorder)
  88469006 | Zellweger syndrome (disorder)

### Expansion

This value set contains 96 concepts

Expansion based on SNOMED CT United States edition 01-Mar 2022

All codes in this table are from the system `http://snomed.info/sct`

Code | Display
267454002 | Acatalasemia (disorder)
238069004 | Acyl-coenzyme A oxidase deficiency (disorder)
363732003 | Addison's disease (disorder)
386584007 | Adrenal cortical hypofunction (disorder)
237735008 | Adrenal Cushing's syndrome (disorder)
65389002 | Adrenoleukodystrophy (disorder)
700463002 | Alpha-methylacyl-CoA racemase deficiency disorder (disorder)
54954004 | Aspartylglucosaminuria (disorder)
238068007 | Bifunctional peroxisomal enzyme deficiency (disorder)
128289001 | Chronic metabolic disorder (disorder)
7573000 | Classical phenylketonuria (disorder)
35691006 | Combined deficiency of sialidase AND beta galactosidase (disorder)
237751000 | Congenital adrenal hyperplasia (disorder)
419097006 | Danon disease (disorder)
124302001 | Deficiency of galactokinase (disorder)
124437004 | Deficiency of glucose-6-phosphatase (disorder)
124335006 | Deficiency of phosphoglycerate kinase (disorder)
124675005 | Deficiency of phosphoglycerate mutase (disorder)
387817006 | Deficiency of phosphorylase b kinase (disorder)
124329006 | Deficiency of phosphorylase kinase (disorder)
46635009 | Diabetes mellitus type 1 (disorder)
44054006 | Diabetes mellitus type 2 (disorder)
73211009 | Diabetes mellitus (disorder)
45744005 | Disorder of mineral metabolism (disorder)
238059005 | Disorder of peroxisomal function (disorder)
238006008 | Disorder of purine and pyrimidine metabolism (disorder)
30171000 | Disorder of adrenal gland (disorder)
73132005 | Disorder of parathyroid gland (disorder)
399244003 | Disorder of pituitary gland (disorder)
190680002 | Disorders of amino acid transport and metabolism (disorder)
16652001 | Fabry's disease (disorder)
79935000 | Farber's lipogranulomatosis (disorder)
717276003 | Folinic acid responsive seizure syndrome (disorder)
20052008 | Fructose-1,6-bisphosphate aldolase B deficiency (disorder)
28183005 | Fructose-biphosphatase deficiency (disorder)
190745006 | Galactosemia (disorder)
192782005 | Galactosylceramide beta-galactosidase deficiency (disorder)
190794006 | Glucosylceramide beta-glucosidase deficiency (disorder)
235908005 | Glycogen storage disease type IX (disorder)
41527003 | Glycogen storage disease type VIII (disorder)
37666005 | Glycogen storage disease type X (disorder)
717821004 | Glycogen storage disease with severe cardiomyopathy due to glycogenin deficiency (disorder)
7265005 | Glycogen storage disease, type I (disorder)
274864009 | Glycogen storage disease, type II (disorder)
66937008 | Glycogen storage disease, type III (disorder)
11179002 | Glycogen storage disease, type IV (disorder)
55912009 | Glycogen storage disease, type V (disorder)
29291001 | Glycogen storage disease, type VI (disorder)
89597008 | Glycogen storage disease, type VII (disorder)
237964009 | Glycogen synthase deficiency (disorder)
61598006 | Glycogenosis with glucoaminophosphaturia (disorder)
238025006 | GM1 gangliosidosis (disorder)
353295004 | Graves' disease (disorder)
21983002 | Hashimoto thyroiditis (disorder)
111578003 | Hereditary nonspherocytic hemolytic anemia due to aldolase A deficiency (disorder)
66999008 | Hyperparathyroidism (disorder)
10649000 | Hyperpituitarism (disorder)
34486009 | Hyperthyroidism (disorder)
36976004 | Hypoparathyroidism (disorder)
74728003 | Hypopituitarism (disorder)
40930008 | Hypothyroidism (disorder)
70199000 | I-cell disease (disorder)
86095007 | Inborn error of metabolism (disorder)
238062008 | Infantile Refsum's disease (disorder)
18756002 | Juvenile GM1 gangliosidosis (disorder)
65524005 | Mannosidosis (disorder)
27718001 | Maple syrup urine disease (disorder)
69463008 | Maroteaux-Lamy syndrome (disorder)
237602007 | Metabolic syndrome X (disorder)
396338004 | Metachromatic leucodystrophy (disorder)
725296006 | Mucolipidosis type IV (disorder)
75610003 | Mucopolysaccharidosis type I (disorder)
65327002 | Mucopolysaccharidosis type I-H (disorder)
26745009 | Mucopolysaccharidosis type I-H/S (disorder)
70737009 | Mucopolysaccharidosis type II (disorder)
73123008 | Mucopolysaccharidosis type I-S (disorder)
43916004 | Mucopolysaccharidosis type VII (disorder)
378007 | Morquio syndrome (disorder)
238061001 | Neonatal adrenoleucodystrophy (disorder)
783717008 | Phosphoglucomutase 1-related congenital disorder of glycosylation (disorder)
5335002 | Phosphoenolpyruvate carboxykinase deficiency (disorder)
25362006 | Phytanic acid storage disease (disorder)
65520001 | Primary hyperoxaluria, type I (disorder)
65764006 | Pseudo-Hurler polydystrophy (disorder)
734434007 | Pyridoxine-dependent epilepsy (disorder)
46683007 | Pyruvate dehydrogenase complex deficiency (disorder)
23849003 | Sandhoff disease (disorder)
88393000 | Sanfilippo syndrome (disorder)
38795005 | Sialidosis (disorder)
58459009 | Sphingomyelin/cholesterol lipidosis (disorder)
34420000 | Storage disease (disorder)
367368009 | Sulfite oxidase deficiency (disorder)
111385000 | Tay-Sachs disease (disorder)
264580006 | Thyroid dysfunction (disorder)
8849004 | Uridine diphosphate glucose-4-epimerase deficiency (disorder)
88469006 | Zellweger syndrome (disorder)

Explanation of the columns that may appear on this page:

Level | A few code lists that FHIR defines are hierarchical - each code is assigned a level. In this scheme, some codes are under other codes, and imply that the code they are under also applies
System | The source of the definition of the code (when the value set draws in codes defined elsewhere)
Code | The code (used as the code in the resource instance)
Display | The display (used in the display element of a Coding). If there is no display, implementers should not simply display the code, but map the concept into their application
Definition | An explanation of the meaning of the concept
Comments | Additional notes about how to use the code