| US Realm | Current Build | Difference | Notes | 
| ValueSets | 
| LOINC Codes | Vital Signs | Comparison | 1 Breaking Change, 0 Changes, 1032 Notes | 
| US Core Status for Smoking Status Observation | ObservationStatus | Comparison | 2 Breaking Changes, 0 Changes, 16 Notes | 
| US Core Smoking Status Observation Codes | Vital Signs | Comparison | 2 Breaking Changes, 0 Changes, 36 Notes | 
| StructureDefinitions | 
| US Core Pediatric BMI for Age Observation Profile | US Core Pediatric Head Occipital-frontal Circumference Percentile Profile | Comparison | 3 Breaking Changes, 2 Changes, 4 Notes | 
| US Core Pediatric Weight for Height Observation Profile | US Core Pediatric Head Occipital-frontal Circumference Percentile Profile | Comparison | 3 Breaking Changes, 2 Changes, 4 Notes | 
| US Core Laboratory Result Observation Profile | US Core Pediatric Head Occipital-frontal Circumference Percentile Profile | Comparison | 8 Breaking Changes, 21 Changes, 4 Notes | 
| US Core Pulse Oximetry Profile | US Core Pediatric Head Occipital-frontal Circumference Percentile Profile | Comparison | 4 Breaking Changes, 5 Changes, 4 Notes | 
| US Core Smoking Status Observation Profile | US Core Pediatric Head Occipital-frontal Circumference Percentile Profile | Comparison | 13 Breaking Changes, 19 Changes, 4 Notes |